LABORATORY INOVATIONS
NUCLEIC ACID ISOLATION ON MAGNETIC BEADS
CHEMAGIC PRIME Junior
CHEMAGIC PRIME Instrument
CHEMAGIC 360 Instrument
CHEMAGIC PREPITO® Instrument
PLATE READER
ENVISION 2105
ENSIGHT™
VICTOR® Nivo™
NEWBORN SCREENING
VICTOR 2D
AutoDELFIA
GSP Instrument
MOLECULAR NEWBORN SCREENING FOR SMA, SCID AND XLA
EONIS System

Nucleic Acid Isolation on Magnetic Beads
CHEMAGIC PRIME Junior
The chemagic Prime Junior instrument enables a streamlined workflow from primary sample to ready to use nucleic acids. Eluate handling such as transfer to storage tubes is included, moreover some deckspace is reserved to fulfll further automation needs in PCR/NGS/Assay set up. It is dedicated for all human related sample materials like blood, plasma, saliva, urine, swabs, feces. Reveal what‘s possible in next generation of automation. With a maximum capacity of 48 samples (4 x 12) from 200 – 1000 µl human body fluids, it is also possible to load sequentially to be most flexible in your daily routine.
Barcode reading ensures full sample traceability
- Automated sample handling eliminates user related variabilities
- M-PVA Magnetic Bead based nucleic acid extraction with preinstalled protocols
- Optimized kits bearing quality, recovery rate and speed in mind
- User-friendly interface and status lights for easy operation
- Deckspace reserved to fulfill automation needs in PCR/NGS/Assay setup
Supported applications
- Genomic DNA and RNA isolation from blood, cells, saliva and tissue for biobanking
- Isolation of viral/bacterial nucleic acids from serum/plasma pools
- Processing human body fluids for research applications
- Extraction of high molecular weight DNA for long range sequencing
- Isolation of DNA from various samples for microbiome analysis

Nucleic Acid Isolation on Magnetic Beads
CHEMAGIC PRIME Instrument
The chemagic™ Prime™ Instrument is a fully automated solution offering hands-free sample transfer, DNA and RNA isolation, normalization (optional), and PCR setup for research applications. This validated, single supplier solution offers high quality DNA and RNA which can be extracted from a variety of matrices. Nucleic acid isolation is a critical prerequisite for many downstream applications. The chemagic Prime Instrument uses patented magnetic bead technology with fully automated liquid handling to provide high quality and high yield extraction of DNA and RNA from a variety of sample types. Extracted nucleic acids are suitable for next generation sequencing, genotyping, MLPA, and other types of PCR analysis. The chemagic Prime separates nucleic acids from solutions by transferring the beads instead of the process solutions, reducing the risk of contamination, offering higher purity and higher molecular weight DNA and RNA than alternative solutions.
Kits are available for DNA and RNA extraction from a variety of human samples including:
- whole bloods
- plasma
- saliva
- FFPE samples
- tissues
- feces
Fully-Automated, Upstream Nucleic Acid Handling
The chemagic Prime Instrument simplifies nucleic acid extraction and analysis by combining our proprietary chemagic extraction technologies with our extensive liquid handling expertise:
- Simplified – Fast, hands-free sample processing
- Reliable – Consistently isolates high quality nucleic acids
- Reproducible – Reduces human error
- Flexible input – 10 µL – 10 mL input amounts
- Trackable – Automated barcode reading
- Flexible throughput – Double sample set capacity increases throughput to 24, 48, or 192 samples
- Flexible output – Various output format options are available
- Precise – VariSpan™ arm and tips improve precision

Nucleic Acid Isolation on Magnetic Beads
CHEMAGIC 360 Instrument
Nucleic Acid Extractor for Medium to High Throughput. Based on our patented chemagen magnetic bead technology the chemagic™ 360 instrument represents the ideal solution for nucleic acid isolation in a huge variety of research market segments including but not limited to Biobanking/Human Genetics, HLA Typing, Virus and Bacteria Detection. Experience the revolutionary compact benchtop design of our newly developed chemagic 360 Nucleic Acid Extractor. Based on the well-established chemagen Technology, the system offers a flexible solution for different sample processing and throughput needs. Configurable with three kinds of chemagic Rod Heads (see table below) the system can process sample volumes from 10 μl – 10 ml.
Features at a glance:
- Bar code reading/sample tracking
- LIMS compatible log files
- Easy navigation and set up
- Pre-installed protocols
- Tracking the progress of a running protocol
- Reduces hands-on time
- Cost-efficient through optimal buffer dispensing
- Fast and reliable membrane pump technology
- Fully integrated in the chemagic 360 software
Chemagic Dispenser 360 unit:
- The use of the chemagic 360 instrument simplifies and improves time consuming sample preparation steps in nucleic acid isolation significantly, by using the chemagic Dispenser 360 unit.
- The chemagic Dispenser 360 notably reduces hands-on time when preparing a chemagic 360 run.
- Independent of the amount of needed buffer, the additional unit prefills tubes/plates quickly and accurately.
- Variants of the chemagic Dispenser 360 unit are available to suit the corresponding chemagic Rod Head formats (12 and 24/96).

Nucleic Acid Isolation on Magnetic Beads
CHEMAGIC PREPITO® Instrument
The chemagic Prepito® is based on Revvity’s proven technology for magnetic bead based DNA/RNA isolation and represents a top quality sample preparation system available as a compact benchtop instrument. Its design is based on many years’ experience in automated nucleic acid isolation gained with the well-established chemagen Technology. In combination with the Prepito Kits, it delivers a high yield of pure DNA/RNA and ensures the success of sensitive research downstream applications like NGS, MLPA, Genotyping, Chip Based Applications and many more.
- High quality DNA/RNA (OD 260/280 1.8, OD 260/230 > 2.0) – suitable for NGS, MLPA, Genotyping
- Chip Based Applications, PCR and many more
- Ready to use DNA/RNA – up to 10 µg DNA/250 µl blood
- Sample volumes up to 1 ml, 1 – 12 samples/run
- Huge kit portfolio – whole blood, saliva, serum/plasma etc.
- Cost efficient – use of standard plastic devices and on-line buffer dispensing instead of expensive cartridges
- Quality assurance – bar code reading/sample tracking and LIMS compatible log files

Multimode Plate Reader
ENVISION 2105
2018 Winner of SelectScience® Seal of Quality Our Alpha and LANCE® reagents are developed and optimized on the EnVision plate reader so you can be confident of accurate results. Plus, we can cite over 15,000 published papers that attest to its real-world performance across a broad range of applications. Our state-of-the-art, dual-detector model is among the fastest HTS readers in the market. Choose from detection technologies including AlphaScreen®, AlphaLISA®, fluorescence, ultra-sensitive luminescence, absorbance, time-resolved fluorescence (TRF) and TR-FRET, for example to detect Revvity’s DELFIA and LANCE assay technologies.
- Time resolved fluorescence certified for use with HTRF® technology
- Maximum speed and sensitivity with proprietary Direct Optics™ technology
- Hybrid system combining filters for sensitivity and monochromators for assay flexibility
- Laser excitation technology for time-resolved fluorescence modes for the best available TRF performance
- Laser technology for high throughput for AlphaScreen assays
- Low detection levels for high throughput screening applications so you can be confident that you are not missing any leads.
- Two configurations are available, which both offer the same unsurpassed sensitivity and analytical performance
Technologies included:
- Filter based fluorescence intensity (top and bottom)
- Time-resolved fluorescence (top and bottom)
- Luminescence, including glow, flash and dual luminescence
- Filter-based absorbance
- Fluorescence Polarization
- Optional technologies
- Standard AlphaLISA®/AlphaScreen®/Alpha
- High-throughput AlphaLISA®/AlphaScreen®/Alpha
- Monochromator-based fluorescence intensity
- Monochromator-based absorbance detection
- Laser-based time-resolved fluorescence
- Ultra-sensitive luminescence
Key Features
- Proprietary Direct Double Optics™ deliver a full lens system for maximum speed and sensitivity (EnVision 2105 HTS system only)
- The fastest mode uses an innovative “on the fly”-detection – making EnVision exceptionally fast in measuring absorbance or fluorescence intensity on a 1536-well plate – less than 36 seconds including plate loading times
- Field upgradeable for changing application needs
- User-changeable, label-specific optical mirror modules and filters for assay customization with positive identification of measurement configuration (barcodes)
- Integrated barcode reading enables barcode reading from short right side and both long sides of the plate
- Optional 21 CFR Part 11 support

Multimode Plate Reader
ENSIGHT™
The EnSight™ multimode plate reader offers HTS Alpha, Ultra-sensitive Luminescence and fast well-imaging technologies alongside conventional multimode detection technologies. Imaging & online data analysis is fast: a 384-well plate can be imaged in less than 5 mins. The system’s modular design, combined with workflow-based Kaleido™ data acquisition & analysis software, gives a truly versatile plate reader that gets users productive quickly. The EnSight system’s cell-imaging option, brings image-based cytometry together with our industry-leading detection technologies for the first time. Imaging is fast, with online data analysis in minutes.
- Well-imaging technology, Alpha technology and conventional multimode detection technologies all on a single benchtop system
- Easily configurable and field upgradable
- Base unit with filter-based absorbance technology and temperature control unit (up to 65°C)
- Eight barcode identified filter positions
- Integrated barcode reading from all four sides of a microplate
- Kaleido™ Data Acquisition and Analysis Software
Technologies:
- Fluorescence well-imaging with single cell resolution for up to four colors (with excitation of three colors in parallel), brightfield and digital phase-contrast imaging
- AlphaLISA® / AlphaScreen® detection with high power laser excitation
- Fluorescence intensity detection (top- and bottom-reading) with monochromator
- Time-resolved fluorescence detection, for example DELFIA® and LANCE® technologies
- Ultra-sensitive luminescence for low signals
- Filter- and optional monochromator-based absorbance detection
Key Features:
- Temperature control to 65°C
- Plate barcode reader
- Plate shaking
- Plate stackers, 20 plates or 50 plates
- Robotic Interface for automation solutions

Microplate Reader
VICTOR® Nivo™
Now with Alpha Technology, the VICTOR® Nivo™ system packs all popular detection modes into the industry’s smallest multimode reader footprint. The perfect microplate reader for everyday biochemical and cell-based assays, it measures at any wavelength, with top and bottom reading of all standard technologies (top only reading for Alpha). Its software interface is easy to learn and use, and lets you control the instrument from almost any device – perfect for multiuser environments. Combine with our assays and reagents to get you started right away.
The VICTOR Nivo system is a high-performance filter-based multimode microplate reader equipped with all major detection technologies:
- Absorbance
- Luminescence
- Fluorescence intensity
- Time-resolved fluorescence
- Fluorescence polarization
- Alpha
- It’s a compact, light-weight multimode plate reader designed for life science research laboratories performing routine low-throughput assays, or assay development work, with diverse application requirements.
Detection Technologies:
- At the heart of the VICTOR Nivo multimode plate reader is a dynamic wheel system with space for up to 32 filters, enabling the detection of a multitude of different dyes. Filters are exchanged between the inner and outer wheels, so any individual filter can serve either the excitation or emission light path. As a result, there’s no need to install new filters when switching between assays, and filters are locked in place, so they can’t get lost in the lab – ideal for multi-user environments. When fully-loaded, the filter system provides the flexibility to detect many dyes with better sensitivity and greater cost-effectiveness than a monochromator.
- For absorbance measurements using the VICTOR Nivo multimode plate reader, there is a choice of either a filter- or a spectrometer-based system. With the spectrometer-based plate reader, full spectrum absorbance measurements are ultra-fast – 230 to 1000 nm at selectable resolutions (2.0 nm, 5.0 nm, 10 nm) in less than 1 second per well.
- Up to eight discrete wavelengths can be detected at once in a single measurement with no wavelength switching, and the spectrometer-based VICTOR Nivo system also allows the detection of a wide range of dyes or measurement of samples with unknown absorbance spectra.
Features & Benefits:
- Compact, lightweight multimode plate reader which frees-up bench space and is easy to move into a biosafety cabinet or another lab
- Internal dynamic filter wheel system, with space for up to 32 filters, provides ready access to filters for a large number of dyes
- For absorbance, choice of filter-based detection for best sensitivity or spectrometer for wavelength flexibility
- Time resolved fluorescence certified for use with HTRF® technology
- Top and bottom reading of all standard technologies (absorbance, luminescence, fluorescence intensity, time-resolved fluorescence and fluorescence polarization), top reading only for Alpha; with high performance for plate formats from 1 to 1536-wells
- Optional dispenser for applications such as fast kinetics, flash luminescence assays, or dual addition assays
- Integrated temperature control (up to 65 °C) and optional gas control unit to keep cells viable during long term kinetic assays
- Browser-based software enables the plate reader to be controlled from a variety of devices – PC, laptop or tablet
- Can be controlled via network or WiFi to facilitate remote working and data access

Newborn screening, Semi-automated system
VICTOR 2D
Since 1999, the semi-automated system has been used in over 200 NBS laboratories all over the world, nearly 10 million newborns are screened with Victor™ 2D each year, it has protocols for seven NBS disorders: congenital hypothyroidism, phenylketonuria, congenital adrenal hyperplasia, galactosemia, cystic fibrosis, biotinidase deficiency and G6PD deficiency.

Newborn screening, plate processor
AutoDELFIA
AutoDELFIA plate processor is an automatic immune-chemical fluorimetric analyzer specially designed and optimized for working with DELFIA test systems in newborn screening. Is the leading neonatal screening platform around the world with more than 300 million screenings to its credit and thousands of children saved.

Newborn screening
The GSP® is a high throughput batch analyzer intended for quantitative or qualitative measurement of neonatal screening samples on 96-well microplates. The instrument is fully automated, performing every stage of an assay from retrieval of the sample plate from the stacker to measurement and reporting of results. Genetic Screening Processor utilizes specific GSP Workstation software for handling of the newborn screening data.
Design of GSP Instrument, software and screening assays offers multiple advantages for your screening program, including:
- Continuous loading of sample allowing more flexible workflows
- Barcoding of all materials to minimize risk of error and hands-on time
- Multi-technology solution to support high sensitivity DELFIA as well as prompt fluorescence measurements
- Extreme ease of use enabling quick user adoption and also rotation of staff duties
- Newborn screening specific informatics bringing the maximum operational efficiency
- Integrated screening operation supporting further growth and change of your program.

Molecular Newborn screening for SMA, SCID and XLA
EONIS System
Simultaneous multiplexing of SMA, SCID & XLA screening from a single DBS punch.
For Laboratory with 20 000 annual samples
- Wallac DBS Puncher
- Inheco Thermoshake
- Multipipette
- Thermo QS DX 96-wel
For Laboratory with 50 000 annual samples
- Panthera-puncher 9 Instrument
- JANUS extraction mini
- Multipipette
- Thermo QS DX 96-wel
For Laboratory with 100 000 annual samples
- Panthera-puncher 9 Instrument
- JANUS Extraction Instrument /JANUS PCR Mastermix
- Thermo QS DX 96-well
- Eonis DNA Extraction Kit
- Eonis SCID-SMA Kit
- Calibrators plateConsumables